Package index • clinicalTrialSimulator

Patients and Allocation Simulation

Functions to simulate patients and their assignment to treatment groups

simulate_patients(): Simulate baseline patient demographics and site assignments

simulate_allocation(): Randomly allocate patients to treatment arms

Outcome Simulation

Functions to simulate different types of clinical outcomes

simulate_outcomes(): Simulate a single outcome per patient (continuous or binary)

simulate_longitudinal_outcomes(): Simulate longitudinal outcome measurements

simulate_survival(): Simulate time-to-event (survival) outcomes

Dropout and Visit Simulation

Functions to simulate events occurring during the study

simulate_visits(): Generate scheduled visits for each patient

simulate_dropout(): Simulate dropouts (patient discontinuation) during the trial

Data

Functions to export data in specific formats

export_adam_format(): Export an ADaM-style ADSL dataset